Effect of Eclipta alba and Ocimum sanctum on haloperidol induced parkinsonism
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چکیده
منابع مشابه
Effect of ethanolic leaf extract of Ocimum sanctum on haloperidol-induced catalepsy in albino mice
Neuroleptic drugs used in the treatment of schizophrenia and other affective disorders are known to produce extrapyramidal side effects. Catalepsy induced by these drugs in Department of Pharmacology, Kasturba Medical College, animals has been used as a model for the extrapyramidal side effects associated with Mangalore 575 001, Karnataka, antipsychotic agents in human beings. In the present st...
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The present experiment was designed to make a systematic study of experimentally induced immunotoxicity of endosulfan and its amelioration with Ocimum sanctum in male Wistar rats at 6, 3 and 1.5 mg / Kg b.wt to groups II, III and IV by mixing in ground nut oil for 6 weeks. To the groups V, VI and VII in addition to endosulfan as above mentioned dose, Ocimum sanctum was given at 200 mg / kg b.wt...
متن کاملEvaluation of aqueous extract of Ocimum sanctum in experimentally induced parkinsonism
Parkinson’s disease (PD) is neurodegenerative disorder characterized by the progressive loss of the dopaminergic neurons in the substantia nigra pars compacta which innervates the dorsal striatum. Using haloperidol induced catalepsy in rat and muscle rigidity in mice effects of aq. extract of Ocimum sanctum (OSEaq) were studied. Haloperidol was administered to induce either short term model (0....
متن کاملEffect of Eclipta Alba on Fructose Induced Hypertension in Albino Rats
ObjectiveHypertension is a common disorder rising in incidence once established treatment is obligatory. The causes, so also the drugs are many & usually the treatment is lifelong. Hence research is going on to find out a suitable & safe drug. Herbal products in this regard are worthy of investigation. Eclipta alba Hassk (Bhringaraja) is recently reported to have diuretic & antihypertensive act...
متن کاملEffect of Ocimum sanctum (OS) leaf extract on hepatotoxicity induced by antitubercular drugs in rats.
Healthy adult albino rats of either sex of Wistar strain weighing 150 to 250 g were used after approval of the Institutional Ethics Committee. They were kept on standard pellet diet and were allowed free access to food and water. The doses of antitubercular drugs (isoniazid (I)-27 mg/kg/day, rifampicin (R)-54 mg/kg/day, pyrazinamide (Z)-135 mg/kg/day) were extrapolated from daily human dose usi...
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ژورنال
عنوان ژورنال: Journal of Drug Delivery and Therapeutics
سال: 2018
ISSN: 2250-1177
DOI: 10.22270/jddt.v8i5.1871